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Vertebrate chromosomes have long (>300 kb) regions of distinct GC richness, repeat content, and gene density, designated isochores in a model of genome organization proposing that genomes are made up of distinct segments of unique composition.

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Vertebrate chromosomes have long (>300 kb) regions of distinct GC richness, repeat content, and gene density, designated isochores in a model of genome organization proposing that genomes are made up of distinct segments of unique composition.

(a) True

(b) False

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This question is from Genome Anatomy topic in division Collecting & Storing Sequences in Laboratory of Bioinformatics

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The correct answer is (a) True

Explanation: Human and mouse chromosomal regions that have a low density of genes are AT-rich and have more Alu or B1/B2 (SINES) than LINE1 elements. Whereas the reverse is true for regions that have a high gene density, and those regions are more GC-rich.

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