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In human normal B and T cells develop the CDC4+ and CDC8+ first and then they differentiate to CDC4+ CDC- and CDC4- CDC+. If there is a defect in development which quadrant in the flow cytometer graph will show more density?

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In human normal B and T cells develop the CDC4+ and CDC8+ first and then they differentiate to CDC4+ CDC- and CDC4- CDC+. If there is a defect in development which quadrant in the flow cytometer graph will show more density?

(a) 1

(b) 2

(c) 3

(d) 4

This question was addressed to me in unit test.

The origin of the question is Flow Cytometry and Cell Sorting topic in division Cancer Biology & Methods in Cytogenetics of Cytogenetics

1 Answer

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Best answer
Right option is (b) 2

Best explanation: Quadrant 2 is the part of the graph where we see both the labels being positive. So in this case mal developement will mean that this quadrant will have higher density.

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