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What is rate-zonal centrifugation?

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What is rate-zonal centrifugation?

(a) Based on separation of particles by mass

(b) Based on separation of particles by density

(c) Based on separation of particles on solubility

(d) Based on separation of particles on size

I have been asked this question in an international level competition.

Query is from Centrifugation topic in portion Unit Operations of Bioprocess Engineering

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Correct answer is (d) Based on separation of particles on size

Explanation: Rate-zonal centrifugation is a centrifugation technique employed to effectively separate particles of different sizes. Once the centrifugation is over, fractions are collected.

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