Question

Which type of fermentation was used by Engineers to produce penicillin on large scale during World War 2?

(a) Semi-Solid Fermentation

(b) Deep-Tank Fermentation

(c) Biphasic Fermentation

(d) Solid-State  Fermentation

I had been asked this question during an internship interview.

My question is based upon The Story of Penicillin:How Biologists and Engineers Work Together in chapter Bioprocess Development of Bioprocess Engineering

Answer 1

The correct choice is (b) Deep-Tank Fermentation

For explanation I would say: The Deep-Tank Batch Fermentation in which there is the application of submerged culture technique which was able to produce Penicillin of Approximately 50mg/ml which grew on large scale during World War 2.