Question

DNA denaturation can occur through ________

(a) Unwinding of DNA double strand

(b) Absorbance of UV rays

(c) Decrease in hydrophobic interactions of base stacking

(d) All of the mentioned

This question was addressed to me in a job interview.

My question is taken from Genes, Chromosomes and Genomes topic in chapter Bioenergetics, Enzymes, Metabolism, Genes, Chromosomes and Genomes of Cell Biology

Answer 1

The correct option is (d) All of the mentioned

For explanation I would say: DNA can denature at high temperature, high or low pH, high salinity, chemical denaturants or enzymes or by physical methods such as excess exposure to UV radiation(or any type of radiation for that matter).