Question

Vertical frame shifts show ______ while the horizontal ones show _______

(a) insertion, insertion

(b) insertion, deletion

(c) deletion, deletion

(d) deletion, insertion

This question was posed to me in unit test.

My question comes from Dot Matrix Sequence Comparison topic in division Sequence Alignment of Bioinformatics

Answer 1

Right choice is (b) insertion, deletion

Best explanation: Deletion and insertion of nucleotides is quite common in alignment process. The dot plot easily represents them with vertical and horizontal shifts. And the mutations are totally out of the diagonal zone.