Question

What is the approximate fraction of genetic variation in the nuclear genome that is expected to have a harmful effect on gene function?

(a) 50%

(b) 25%

(c) 10%

(d) 1%

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This interesting question is from Genes, Chromosomes and Genomes topic in division Bioenergetics, Enzymes, Metabolism, Genes, Chromosomes and Genomes of Cell Biology

Answer 1

Correct choice is (d) 1%

Explanation: Genetic variation due to mutation causes harmful effects on gene function. Ad low as 1% genetic variation can cause noticeable harmful changes the expression and function of genes. It may lead to congenital diseases or may be fatal.