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Which enzymes are responsible for detoxification of organic compounds carried out by the smooth endoplasmic reticulum?

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Which enzymes are responsible for detoxification of organic compounds carried out by the smooth endoplasmic reticulum?

(a) Dehydrogenases

(b) Oxygenases

(c) Nucleases

(d) Ribonucleases

The question was posed to me in an interview for job.

My doubt stems from Cytoplasmic Membrane Systems in chapter Cytoplasmic Membrane Systems of Cell Biology

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The correct answer is (b) Oxygenases

To explain I would say: Oxygen transferring enzymes – oxygenases (including cytochrome P450) carry out the detoxification of organic compounds and are synthesized in the smooth endoplasmic reticulum.

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