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Which of the following disease associated with the nervous system is caused by disorder in gap junctions?

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Which of the following disease associated with the nervous system is caused by disorder in gap junctions?

(a) Parkinson’s disease

(b) Brain ischemia

(c) Stroke

(d) Seizures

This question was addressed to me during an interview.

The doubt is from Extracellular Matrix and Cell Interactions topic in division Extracellular Matrix and Cell Interactions of Cell Biology

1 Answer

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Right answer is (b) Brain ischemia

The explanation is: Brain ischemia, otherwise known cerebral ischemia where the blood flow to the brain is constricted. The gap junctions are unable to provide oxygen thus the brain undergoes hypoxia. This situation is permanent if it is untreated for prolonged time.

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