Question

Myoglobin binding of O2 depends on ___________

(a) Hemoglobin concentration

(b) O2 concentration and affinity of myoglobin for O2

(c) Ka

(d) Kd

I have been asked this question in an interview for job.

Enquiry is from Reversible Binding of a Protein to a Ligand: Oxygen-Binding Proteins in division Three Dimensional Structure Of Proteins and Protein Function of Biochemistry

Answer 1

Correct choice is (b) O2 concentration and affinity of myoglobin for O2

To explain: Myoglobin binding of O2  depends on pO2  and its affinity for O2.