Question

Which of the following statements are true about the reactions at the active center of chymotrypsin?

(a) The aspartate residue gives an electron to histidine

(b) The aspartate residue gives a proton to histidine

(c) The aspartate residue keeps the histidine in the correct direction

(d) A proton moves from the aspartate to serine to histidine in the catalytic triad of chymotrypsin

This question was posed to me in an online interview.

The query is from Examples Of Enzymatic actions in division Enzymes, Carbohydrates and Gycobiology of Biochemistry

Answer 1

The correct answer is (c) The aspartate residue keeps the histidine in the correct direction

For explanation I would say: Aspartate residue accepts a proton from serine.