Question

In Rosetta, The segments with assigned _______ structures are subsequently assembled into a ______ dimensional configuration.

(a) primary, three

(b) secondary, three

(c) secondary, two

(d) primary, three

I got this question in an online interview.

My doubt is from Ab Initio Protein Structural Prediction & Homology Modeling in division Protein Tertiary Structure Prediction of Bioinformatics

Answer 1

Correct answer is (b) secondary, three

To explain I would say: Through random combinations of the fragments, a large number of models are built and their overall energy potentials calculated. The conformation with the lowest global free energy is chosen as the best model.