Question

For which of the following organelles, the proteins to be imported remain in their native folded state?

(a) Peroxisomes

(b) Mitochondrion

(c) Chloroplast

(d) Endoplasmic reticulum

The question was posed to me at a job interview.

This intriguing question comes from Cytoplasmic Membrane Systems in division Cytoplasmic Membrane Systems of Cell Biology

Answer 1

The correct option is (a) Peroxisomes

To elaborate: Proteins carrying a peroxisomal targeting signal (PTS) bind to the PTS receptors, present on the membrane surface, which escort the protein through the boundary membrane to the internal matrix, in its native folded state.