Question

According to Chargaff’s rule, in a DNA molecule ____________

(a) The amount of adenine and thymine is equal to the amount of guanine and cytosine

(b) The amount of adenine and guanine is equal to the amount of thymine and cytosine

(c) The amount of adenine and uracil is equal to the amount of guanine and cytosine

(d) The amount of adenine and guanine is equal to the amount of uracil and cytosine

This question was addressed to me during an internship interview.

This is a very interesting question from Nucleic Acid Structure topic in chapter Nucleotides and Nucleic Acids of Biochemistry

Answer 1

Correct option is (a) The amount of adenine and thymine is equal to the amount of guanine and cytosine

Explanation: According to Chargaff’s rule, whatever the amount of adenine, it is equal to the amount of thymine and same is the case with guanine and cytosine.