Question

What do you mean by the term “Back mutation”?

(a) Mutant to wild type

(b) Mutant from wild type

(c) Mutant from normal type

(d) Mutant forward from wild type

The question was posed to me during an internship interview.

I'd like to ask this question from Comparison of Batch and Continuous Culture in Industrial Processes topic in portion Microbial Growth Kinetics of Bioprocess Engineering

Answer 1

The correct option is (a) Mutant to wild type

The explanation: Mutation can occur in two directions; mutation from wild type to mutant is called a forward mutation, and mutation from mutant to wild type is called a back mutation or reversion. Reverse mutation from the aberrant state of a gene back to its normal, or wild type, state can result in a number of possible molecular changes at the protein level. True reversion is the reversal of the original nucleotide change.