Question

Which of the following is a short-lived messenger that acts by stimulating a soluble guanylyl cyclase, raising [cGMP] and stimulating PKG?

(a) NO

(b) NO2

(c) NO3^–

(d) N2O

This question was posed to me in an interview.

This key question is from Receptor Enzymes topic in chapter Biosignalling of Biochemistry

Answer 1

Right answer is (a) NO

To explain I would say: NO is a short-lived messenger that acts by stimulating a soluble guanylyl cyclase, raising [cGMP] and stimulating PKG.