Question

At which cell cycle checkpoint, cell cycle is halted if cell’s DNA is damaged?

(a) G1 – S

(b) S – G2

(c) G2 – M

(d) G0 – G1

I got this question during an interview.

Asked question is from Regulation of the Cell Cycle by Protein Kinases topic in division Biosignalling of Biochemistry

Answer 1

Right answer is (a) G1 – S

Best explanation: During G1 phase cell grows and during S phase DNA replicates. So there must be a checkpoint between these two phases to check if there is a damage in DNA.