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Which out of the following statements is true about G-protein couple receptors?

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in Biochemistry by (89.2k points)
Which out of the following statements is true about G-protein couple receptors?

(a) The N-terminal chain is extracellular and C-terminal chain is intracellular

(b) It contains 5 trans-membrane hydrophobic sections

(c) There are more extracellular loops than intracellular loops

(d) The binding region for G-protein involves 2 extracellular loops

The question was posed to me in an online interview.

The origin of the question is G Protein in chapter Biosignalling of Biochemistry

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Best answer
Correct answer is (a) The N-terminal chain is extracellular and C-terminal chain is intracellular

Best explanation: GPCR is characterized by an extracellular N-terminus and an intracellular C-terminus.

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