Question

Which of the following is false about purine and pyrimidine bases?

(a) They are hydrophobic and relatively insoluble in water at the near-neutral pH of the cell

(b) At acidic or alkaline pH the bases become charged and their solubility in water increases

(c) Purines have two rings in their structure, but pyrimidine bases have only one ring

(d) At acidic or alkaline pH the bases become charged and their solubility in water decreases

This question was addressed to me in homework.

I need to ask this question from Nucleotides & Nucleic Acids Basics in portion Nucleotides and Nucleic Acids of Biochemistry

Answer 1

Correct answer is (d) At acidic or alkaline pH the bases become charged and their solubility in water decreases

Best explanation: At acidic or alkaline pH the bases become charged and their solubility in water increases.