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Persistence of the plaque can lead to ____________

i. embolism    ii. stroke     iii. paralysis    iv. diabetes   v. coronary thrombosis    vi. Alzheimer’s  vii. vessel rupture  viii. Dementia

(a) i, iv, v, viii

(b) i, ii, v, vii

(c) vi, viii

(d) iii, v, viii

I got this question during a job interview.

My question is taken from Angioplasty topic in chapter Diagnostic Investigation in Neurology and Cardiology of Clinical Science

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The correct option is (b) i, ii, v, vii

To explain I would say: Embolism and Stroke are situations when a clot has gotten stuck in a blood vessel. This happens because the plaque deposition does not allow the blood to flow freely so some cells may start depositing and coagulating by the capillary wall forming a thrombus (blood clot).  Stroke is for the brain while embolism is for a heart. Embolism leads to coronary thrombosis (heart attack). Plaque deposition causes the heart to beat with more force to allow blood flow leading to coronary thrombosis.  The deposition of plaque puts more pressure on the walls of the vessels which can cause wall rupture.

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