Question

Which of the following is the major point of regulation on the pathway to cholesterol?

(a) Thiolase

(b) HMG co-A synthase

(c) HMG co-A reductase

(d) Pyruvate kinase

I had been asked this question during a job interview.

The doubt is from Biosynthesis of Cholesterol, Steroids and Isoprenoids in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry

Answer 1

The correct option is (c) HMG co-A reductase

To explain I would say: HMG co-A reductase is the major point of regulation on the pathway to cholesterol.