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In the first committed step of pyrimidine biosynthesis, the reaction is catalyzed by ____________

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In the first committed step of pyrimidine biosynthesis, the reaction is catalyzed by ____________

(a) Adenylate kinase

(b) Aspartate transcarbamoylase

(c) Dihyhroorotase

(d) Cytidylate synthase

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Question is from Biosynthesis and Degradation of Nucleotides topic in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry

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Correct answer is (b) Aspartate transcarbamoylase

To explain I would say: Carbamoyl phosphate reacts with aspartate to yield N-carbamoylaspartate in the first committed step of pyrimidine biosynthesis catalyzed by aspartate transcarbamoylase.

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