Question

Which of the following is true about RNA synthesis?

(a) Synthesis of RNA is always in the 5’ to 3’ direction

(b) RNA polymerase requires a primer for initiating transcription

(c) U is inserted opposite T in transcription

(d) New nucleotides are added on the 2’-OH of the ribose sugar

The question was asked during an online interview.

The above asked question is from DNA-Dependent Synthesis of RNA topic in division DNA, RNA and Protein Metabolism of Biochemistry

Answer 1

Correct answer is (a) Synthesis of RNA is always in the 5’ to 3’ direction

Explanation: Unlike DNA polymerase, RNA polymerase does not require a primer to initiate transcription.