Question

In which of the following cases the first base of anticodon pairs with only one codon?

(a) When the first base of anticodon is A or C

(b) When the first base of anticodon is A or G

(c) When the first base of anticodon is inosine

(d) When the first base of anticodon is G or U

I have been asked this question in an online interview.

This intriguing question comes from The Genetic Code in portion DNA, RNA and Protein Metabolism of Biochemistry

Answer 1

Right option is (a) When the first base of anticodon is A or C

The best I can explain: When the first base of the anticodon is C or A, base pairing is specific and only one codon is recognized by that t-RNA.