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Which of the following is a measure of the effect of an enzyme’s concentration on flux through a multi-enzyme pathway?

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Which of the following is a measure of the effect of an enzyme’s concentration on flux through a multi-enzyme pathway?

(a) Response coefficient

(b) Elasticity coefficient

(c) Flux control coefficient

(d) Metabolic control

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Origin of the question is Analysis of Metabolic Control in portion Principles of Metabolic Regulation: Glucose and Glycogen of Biochemistry

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Correct choice is (c) Flux control coefficient

For explanation: Elasticity coefficient is a measure of how responsive the enzyme is to changes in the concentration of a metabolite.

An expression for the experimentally determined change in flux through a pathway in response to a regulatory hormone or second messenger is the response coefficient.

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