Question

If mitochondria were blocked at the site of NADH oxidation and were treated with succinate as substrate, what would the P : O ratio is?

(a) Same as that normally produced by succinate

(b) One more than normally produced by succinate

(c) One less than normally produced by succinate

(d) Zero

The question was posed to me at a job interview.

The above asked question is from ATP Synthesis-1 in chapter Oxidative Phosphorylation and Photophosphorylation of Biochemistry

Answer 1

The correct option is (a) Same as that normally produced by succinate

The best I can explain: If mitochondria were blocked at the site of NADH oxidation and were treated with succinate as substrate, the P : O ratio is the same as that normally produced by succinate.