Question

An alternative method is to produce an odds scoring matrix calculated by dividing each base frequency by the background frequency of that base.

(a) True

(b) False

I have been asked this question in semester exam.

I need to ask this question from Statistical Methods for Aiding Alignment topic in portion Multiple Sequence Alignment of Bioinformatics

Answer 1

The correct answer is (a) True

For explanation: In this method, the probability of each location is then found by multiplying the odds scores from each column. An even simpler method is to use log odds scores in the matrix. The column scores are then simply added. In this case, the log odds scores must be converted to odds scores before position probabilities are calculated.