Question

In Jukes–Cantor Model to correct evolutionary distances, A formula for deriving evolutionary distances that include hidden changes is introduced by using a logarithmic function. It is ____

(a) dAB = −(3/4) log[1 − (4/7)pAB]

(b) dAB = −(3/4) ln[1 − (5/3)pAB]

(c) dAB = −(3/4) log[1 − (4/3)pAB]

(d) dAB = −(3/4) ln[1 − (4/3)pAB]

The question was posed to me in final exam.

The doubt is from Forms of Tree Representation in section Molecular Phylogenetics of Bioinformatics

Answer 1

Right option is (d) dAB = −(3/4) ln[1 − (4/3)pAB]

Best explanation: The simplest nucleotide substitution model is the Jukes–Cantor model, which assumes that all nucleotides are substituted with equal probability. dAB is the evolutionary distance between sequences A and B and p AB is the observed sequence distance measured by the proportion of substitutions over the entire length of the alignment.