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The choice of a suitable multiple sequence alignment method depends on the degree of variation among the sequences.

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The choice of a suitable multiple sequence alignment method depends on the degree of variation among the sequences.

(a) True

(b) False

I have been asked this question in quiz.

The origin of the question is Reliability of Phylogenetic Predictions in portion Phylogenetic Tree Construction Methods and Programs of Bioinformatics

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The correct answer is (a) True

For explanation I would say: The degree of variation also sometimes affecs the efficiency and nature of output. Once a suitable alignment has been found, one may also ask how well the predicted phylogenetic relationships are supported by the data in the multiple sequence alignment.

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