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PHYML is a web-based _______ program using the _____

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PHYML is a web-based _______ program using the _____

(a) phylogenetic, GA (Genetic Algorithm)

(b) sequence based alignment, GA (Genetic Algorithm)

(c) phylogenetic, dynamic programming

(d) sequence based alignment, dynamic programming

I had been asked this question in an online interview.

The query is from Phylogenetic Programs topic in portion Phylogenetic Tree Construction Methods and Programs of Bioinformatics

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Correct option is (a) phylogenetic, GA (Genetic Algorithm)

To explain: It first builds an NJ tree. Further it uses it as a starting tree for subsequent iterative refinement through subtree swapping. Branch lengths are simultaneously optimized during this process.

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