Question

Which of the following is incorrect statement about the Kimura model?

(a) It is a model to correct evolutionary distances and  is a more sophisticated model

(b) In this, the mutation rates for transitions and transversion are assumed to be different

(c) According to this model, occur more frequently than transversions

(d) According to this model, transversions occur more frequently than transitions

This question was posed to me by my school principal while I was bunking the class.

I'm obligated to ask this question of Gene Phylogeny Versus Species Phylogeny in division Molecular Phylogenetics of Bioinformatics

Answer 1

The correct option is (d) According to this model, transversions occur more frequently than transitions

Easiest explanation: This provides a more realistic estimate of evolutionary distances. The Kimura model uses the following formula dAB = −(1/2) ln(1 − 2pti − ptv) − (1/4) ln(1 − 2ptv). dAB is the evolutionary distance between sequences Aand B, pti is the observed frequency for transition, and ptv the  frequency of transversion.