Question

In Genome-wide prediction of protein functions by a combinatorial method– Each point represents a protein, and branches between proteins indicate a relationship by one of several criteria indicated in the legend.

(a) True

(b) False

The question was asked in class test.

My question is taken from Prediction of Gene Function Based on a Composite Analysis topic in division Genome Analysis of Bioinformatics

Answer 1

Correct choice is (a) True

Explanation: Branch lengths are shorter for closely related proteins and thicker when two or more prediction methods indicate a relationship. The links are based on experimental data, proteins whose homologs are known to operate sequentially in metabolic pathways, proteins that evolved in a correlated fashion as evidenced by presence in fully sequenced genomes, proteins whose homologs are fused into a single protein in another organism, and proteins whose mRNA expression profiles are similar under a range of cellular and environmental conditions.