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The Philadelphia chromosome is the best studied example of ________________

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The Philadelphia chromosome is the best studied example of ________________

(a) inversion

(b) translocation

(c) deletion

(d) duplication

I got this question during an online exam.

My question is based upon Gene Expression Control in section Control of Gene Expression of Cell Biology

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Right answer is (b) translocation

For explanation: Philadelphia chromosome is the best studied example of translocation. It is a chromosome found in the malignant cells of leukemia patients. The Philadelphia chromosome was discovered in 1990 and is a shortened version of human chromosome 22.

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