The correct answer is:
(c) 1875
Explanation:
The connection between cancer and environmental factors, such as carcinogens in the environment, began to be recognized in the late 19th century. One of the earliest observations of this correlation was in 1875 when Sir Percival Pott, a British surgeon, made a notable connection between cancer and environmental exposures. He documented that chimney sweeps had a high incidence of scrotal cancer, likely due to prolonged exposure to soot. This was one of the first links made between cancer and environmental carcinogens.