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Importance of transcription factors in embryonic stem cells was demonstrated in ______________

(a) 1990

(b) 1994

(c) 2000

(d) 2006

This question was addressed to me by my college professor while I was bunking the class.

My doubt stems from Gene Expression Control in section Control of Gene Expression of Cell Biology

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Right answer is (d) 2006

Easy explanation: Stem cells from chicken and murine embryos were extensively studied by Shinya Yamanaka and Kazutoshi Takahashi and in 2006 they published a paper regarding the role of transcription factors in stem cells.

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