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Perforins and granzymes are secreted by ______________________

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Perforins and granzymes are secreted by ______________________

(a) Cytotoxic T lymphocytes

(b) Helper T lymphocytes

(c) Regulatory T lymphocytes

(d) B lymphocytes

I had been asked this question in a job interview.

The query is from Immune Response in division Immune Response of Cell Biology

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Correct choice is (a) Cytotoxic T lymphocytes

The best I can explain: Cytotoxic T lymphocytes patrol the body and screen cells for abnormalities. The CTLs secrete perforins in tightly enclosed space between cells that leads to the formation of transmembrane channels through which the granzymes enter the cells and direct them to apoptosis.

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