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T-cells are activated by _______________

(a) autoantibodies

(b) antibodies

(c) fragments of antigens

(d) intact antigens

I have been asked this question during an online exam.

I'd like to ask this question from Immune Response in chapter Immune Response of Cell Biology

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Right answer is (c) fragments of antigens

The explanation: Unlike B-cells, T-cells do not require intact antigens for activation rather small fragments of antigens. The antigen-presenting cells display fragments of antigens on their surfaces that can be recognized by the T-cell receptors.

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