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You can see non-cannonical base pairing in________

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You can see non-cannonical base pairing in________

(a) dsDNA

(b) ssDNA

(c) dsRNA

(d) ssRNA

This question was posed to me in an interview.

This is a very interesting question from Transcription in Prokaryotes : Termination in portion Gene Expression : Transcription Prokaryotes of Cytogenetics

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Correct choice is (c) dsRNA

Easy explanation: Along with canonical base pairing with the normal base pairs according to Watson-Crick rules, dsRNA also forms non-cannonical base pairs. However, dsDNA can’t do so. ssRNA and ssDNA are called so because they are single stranded so there is no base pairing at all.

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