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Which of the following is retained in the C complex of splicosome?

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Which of the following is retained in the C complex of splicosome?

(a) U5

(b) U4

(c) U2AF

(d) U1

The question was posed to me in an interview for internship.

My doubt stems from Post-Transcriptional Modification topic in portion Gene Expression : Transcription Prokaryotes of Cytogenetics

1 Answer

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Right choice is (a) U5

To explain I would say: The C complex is the final structure before the attack. Then U6 has replaced U1 and U2 has replaced U2AF and U4 dissociates. Only U5 is still there stabilizing the structure by binding the two ends to close.

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