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Nitrazepam a weak base, will be in which form in the stomach?

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Nitrazepam a weak base, will be in which form in the stomach?

(a) Ionized form mostly

(b) Non-ionized form mostly

(c) Half ionized and half no ionized

(d) Will form aggregate

I have been asked this question in examination.

I'd like to ask this question from Drugs Absorption in division Absorption of Drugs of Drug Biotechnology

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Correct answer is (a) Ionized form mostly

Explanation: The pH of the stomach is 1.5. Nitrazepam being a weak base will be in an ionized form in the stomach. In plasma and small intestine with pH 7.4 and 5 respectively, Nitrazepam will be in unionized form.

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