Question

Which of the following is not true about plasmids?

(a) They are extrachromosomal DNA

(b) They are double stranded

(c) They confer antibiotic resistance

(d) They may get incorporated in chromosome

I have been asked this question during a job interview.

My question comes from Plasmids in portion Genomics : The Mapping and Sequencing of Genomes of Cytogenetics

Answer 1

Correct choice is (d) They may get incorporated in chromosome

For explanation: Plasmids generally don’t get incorporated in a chromosome; if it does so then it is known as episome not plasmids. It is true that plasmids are circular, double stranded, extrachromosomal DNA that can confer antibiotic resistance.