Question

I^A allele codes for the _________________ while I^B codes for _________________

(a) Alpha N galactosamine transferase, galactose transferase

(b) Glycosamino glycan transferase, Alpha N glucosamine transferase

(c) Alpha glucosamine transferase, Alpha galactosamine transferase

(d) Galactose transferase, galactose transferase

I have been asked this question during an online interview.

My question is from Multiple Alleles in section Extension and Deviation from Mendelian Genetic Principles of Cytogenetics

Answer 1

Correct option is (a) Alpha N galactosamine transferase, galactose transferase

Best explanation: The IA allele produces a glycosyltransferase enzyme that adds the sugar α N-acetyl galacto-samine to the polysaccharide to produce the A antigen. The I^B allele produces a different glycolsyl transferase enzyme that adds the sugar galactose to produce the B antigen.