Ask a Question
  • Home
  • Cytogenetics
  • If there is an improper attachment of spindle fiber, which protein sends the negative signal?

If there is an improper attachment of spindle fiber, which protein sends the negative signal?

← Prev Question Next Question →
+1 vote
105 views
in Cytogenetics by (679k points)
If there is an improper attachment of spindle fiber, which protein sends the negative signal?

(a) Mcm

(b) Mdm2

(c) Mad2

(d) Mek

The question was posed to me in an interview for job.

My enquiry is from Meiosis Prophase 1 : Zygotene topic in chapter Chromosomal Changes During Meiosis of Cytogenetics

1 Answer

+1 vote
by (1.6m points)
selected by
 
Best answer
Right option is (c) Mad2

The best explanation: Mad2 is responsible for signalling improper binding of the spindle fiber to the centromere. This negative signal prevents apoptosis. Mdm2 is linked to p53 while Mcm activates ORC. Mek is a part of monomeric G protein signaling.

Related questions

Welcome to TalkJarvis QnA, a question-answer community website for the people by the people. On TalkJarvis QnA you can ask your doubts, curiosity, questions and whatever going in your mind either related to studies or others. Experts and people from different fields will answer.

Most popular tags

biology – class 12 biology – class 11 construction & building materials chemistry – class 12 electronic devices & circuits network theory data structures & algorithms ii cell biology ic engine insurance finance money computational fluid dynamics engineering physics i discrete mathematics chemistry – class 11 aerodynamics casting-forming-welding i engineering mathematics operating system casting-forming-welding ii engineering drawing mysql engineering geology digital circuits wireless mobile energy management electrical measurements digital communications cyber security analytical instrumentation embedded systems electric drives cytogenetics advanced machining computer fundamentals life sciences basic civil engineering iot design of electrical machines physics – class 12 applied chemistry dairy engineering basic chemical engineering cloud computing microprocessor bioinformatics aircraft design aircraft maintenance software engineering drug biotechnology digital signal processing biochemistry data structures & algorithms i automotive engine design avionics engineering material & metallurgy energy engineering cognitive radio unix electrical machines biomedical instrumentation object oriented programming electromagnetic theory power electronics analog communications bioprocess engineering civil engineering drawing engineering metrology physics – class 11 mathematics – class 12 engineering chemistry i basic electrical engineering unit processes mongodb signals and systems cryptograph & network security hadoop mathematics – class 11 engineering physics ii html control systems engineering mechanics antennas analog circuits computer network java sql server javascript concrete technology chemical process calculation artificial intelligence design of steel structures c++ database management computer architecture engineering chemistry ii corrosion engineering chemical technology dc machines
Powered by TalkJarvis
...