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Conjugation can’t take place between ___________

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Conjugation can’t take place between ___________

(a) F- and F+

(b) F’ and F-

(c) HFR and F-

(d) HFR and F+

The question was asked during an online interview.

Question is taken from Genetic Recombination topic in division Genetic Recombination of Drug Biotechnology

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Correct choice is (d) HFR and F+

The explanation is: For conjugation to take place one bacterium must have the F plasmid and others should lack it. HFR has the components of F plasmid within its genome so it can’t mate with another F+.

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