Question

Which of the following is INCORRECT for the lock-and-key model?

(a) It is used to describe the binding process

(b) The active site of the enzyme is complementary to the substrate

(c) It demonstrates enzyme-substrate complex

(d) The binding of the substrate produces a conformational change in enzyme

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This is a very interesting question from Enzymes in division Biomolecules and Catalysis of Life Sciences

Answer 1

Correct answer is (d) The binding of the substrate produces a conformational change in enzyme

Explanation: Lock-and-key model is used to describe the enzyme-substrate complex. It is the binding process where the active site of an enzyme is complementary to the shape of the substrate. The binding of the substrate produces a conformational change in the enzyme is incorrect as the confirmation of enzyme changes only in the induced fit model.