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Which part of the nucleotide is responsible for the formation of bonds in DNA double helix?

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in Chemistry – Class 12 by (188k points)
Which part of the nucleotide is responsible for the formation of bonds in DNA double helix?

(a) Base

(b) Sugar

(c) Phosphate group

(d) Hydroxyl group of sugar

This question was addressed to me in an interview for internship.

This interesting question is from Biomolecules in portion Biomolecules of Chemistry – Class 12

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Right answer is (a) Base

To explain: In a DNA strand, the bases protrude outward whereas the sugar and phosphate lie in a straight chain. The bases pair up in specific pair through hydrogen bonds to form a double helix. Adenine forms two hydrogen bonds with thymine, whereas cytosine forms three hydrogen bonds with guanine.

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