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How many steps of decarboxylation lead to the formation of ketoglutaric acid?

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in Biology – Class 11 by (272k points)
How many steps of decarboxylation lead to the formation of ketoglutaric acid?

(a) One

(b) Three

(c) Two

(d) Seven

This question was posed to me during an internship interview.

This is a very interesting question from Aerobic Respiration topic in portion Respiration in Plants of Biology – Class 11

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Correct option is (c) Two

For explanation I would say: Two steps of decarboxylation leads to the formation of ketoglutaric acid. When citric acid is formed in the cycle, it then forms cis-acotinic acid and then isocitric acid. Isocitric acid further forms oxalosuccinic acid which finally forms ketoglutaric acid in the presence of oxalosuccinate decarboxylase enzyme.

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