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Accumulation of which of the following in the brain leads to phenylketonuria?

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in Biology – Class 12 by (271k points)
Accumulation of which of the following in the brain leads to phenylketonuria?

(a) Phenylpyruvic acid

(b) Pyruvic acids

(c) Tyrosine

(d) Phenylalanine

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This interesting question is from Inheritance Principles topic in portion Principles of Inheritance and Variation of Biology – Class 12

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Right answer is (d) Phenylalanine

Best explanation: Phenylketonuria is caused due to the accumulation of phenylalanine in the brain of the affected individuals. Phenylalanine and its derivative are also excreted through the urine because they are poorly absorbed by the kidneys.

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