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Which of the following chemical mutagen is both mutagenic to replicating and non-replicating DNA?

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in Biology – Class 12 by (271k points)
Which of the following chemical mutagen is both mutagenic to replicating and non-replicating DNA?

(a) Acridines

(b) Nitrous acid

(c) Base analogs

(d) Mustard gas

I had been asked this question in a job interview.

Enquiry is from Inheritance and Variation Principles topic in section Principles of Inheritance and Variation of Biology – Class 12

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Correct answer is (b) Nitrous acid

The explanation: Nitrous acid is the chemical mutagen that is both mutagenic to replicating and non-replicating DNA. Acridines are very powerful mutagens and they induce frame shift-mutation or gibberish mutation.

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