Question

Heterozygous individuals of sickle cell anaemia are severely affected by the disease.

(a) False

(b) True

I have been asked this question during an interview for a job.

My question comes from Inheritance and Variation Principles in chapter Principles of Inheritance and Variation of Biology – Class 12

Answer 1

The correct answer is (a) False

The best I can explain: No, heterozygous individuals of sickle cell anaemia are not severely affected by the disease. Apparently, they appear to be unaffected by the disease. But, there is a 50% probability of transmission of the mutant gene to the progeny.